Cracking the code of the Disulfide bond 

Glutathione is literally in every cell of the human body. Glutathione was discovered in 1888 by J. de Rey-Pailhade. However, its bodily replenishment was often hindered by synthesis complexities and by the inability of the rate-limiting L-Cysteine to arrive safely into cells to participate in the synthesis of Glutathione. As it is a tripeptide, Glutathione is composed of three amino acids: L­Cysteine, a Glutamate source, and Glycine.

For years, many scientists thought that the disulfide bond of L-Cysteine was so strong, that once it is locked, in an oxidized state, this amino acid was being prepared for excretion.

In a lab at Harvard, Dr. Albert Crum discovered that the disulfide bond is physiologically reversible under substrate-specific enzymes that exist in the cytosol of each cell.   Dr. Crum also discovered:

  • that the oxidized state can be a carrier and protector of L-Cysteines. Although an oxidized molecule itself, it saved the L­Cysteine from irreversible oxidation to the compounds: Sulfenic acid, Sulfinic acid and Sulfonic acid and their excretion.
  • The disulfide bond is also capable of holding in reserve and preserving additional molecules of L-Cysteine via an electron transfer coupling mechanism. 
  • As a biomarker of Oxidative Stress, the disulfide bond can also signal the genome for genomic intervention commensurate with the immunological challenge being confronted.

By understanding the reverse-engineering process of the Cystine and Cysteine molecules, what before was known as a pleiotropic paradox, was now solved.  In biochemistry, this is called the precursor method:  a chemical compound preceding another in a metabolic pathway.  This discovery is what also makes IF200 patented.

Find Your Answers at Three Aminos Today

Our team of researchers and medical professionals at Three Aminos have dedicated years to researching and producing the best antioxidant supplement available today. Our Immune Formulation 200® is a revolutionary combination of three amino acids and selenium, which are all ingredients your body needs to produce the powerful antioxidant, intracellular glutathione. It is not just simply an antioxidant supplement, but a supplement containing the ingredients that allow your body to produce its own antioxidants at the cellular level. This way, your body is in control of how little or how much it needs to make.

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